During neuronal degenerative diseases, neuronal microcircuits undergo severe structural alterations, leading to remodeling of synaptic connectivity.The functional consequences of such remodeling are mostly unknown.For instance, in mutant rd1 mouse retina, a common model for Retinitis Pigmentosa, rod bipolar cells (RBCs) establish contacts with remn
The Spectral Optimization of a Commercializable Multi-Channel LED Panel With Circadian Impact
There exists a need for the design of light emitting diode AEG IWE41600KB INDUCTION WOK ACTIVE TOUCH (LED) luminaires which can deliver both visual and non-visual benefits of light to humans.In this work, we introduce an optimization approach based on spectral shaping for a minimalistic and practical design of a circadian-tunable multi-channel lumi
Proactive In-Water Ship Hull Grooming as a Method to Reduce the Environmental Footprint of Ships
The application of a proactive grooming program to manage the fouling control coatings applied to ship hulls provides an opportunity to address the climate crisis, invasive species and the discharge Pourover Coffee Machines of biocides into the marine environment.A large percentage of the total power required to propel a ship is to overcome the vis
The Inconceivability Argument
This paper develops and defends a new argument against physicalist views of consciousness: the inconceivability argument.The argument has two main premises.First, it is not (ideally, positively) conceivable that phenomenal truths are grounded in physical truths.(For example, one cannot positively conceive of a situation in Pourover Coffee Machines